Manning completed 27-of-42 passes (64.3%) for 462 yards with seven touchdowns (141.1 rtg.) in Denver’s 49-27 season-opening win against the defending Super Bowl-champion Baltimore Ravens. His seven touchdowns matched the NFL record (last accomplished by Minnesota’s Joe Kapp in 1969) and his 462 yards tied for the third-highest single-game total in Broncos history.
He became the first player to connect for multiple touchdowns with three different targets, tossing two scoring passes apiece to tight end Julius Thomas as well as wide receivers Demaryius Thomas and Wes Welker.
Denver’s 49-point output against the Ravens tied for the second-highest scoring total in team history, as Manning’s five second-half touchdowns helped turn a 17-14 halftime deficit into a 22-point win.
His accomplishment marks the 24th such award of his career, passing Patriots quarterback Tom Brady for the most all-time. It’s the third time he has earned the honor with Denver (Weeks 6, 17 in 2012) and the 49th time a Broncos player has taken home the award.
MOST CONFERENCE PLAYER OF THE WEEK AWARDS, NFL HISTORY
| Player | No. | |
| 1. | Peyton Manning* | 24 |
| 2. | Tom Brady* | 23 |
| 3. | Dan Marino | 18 |
| 4. | Drew Brees* | 16 |
| Brett Favre | 16 | |
| 6. | John Elway | 15 |
| *Active |
PEYTON MANNING’S CAREER AFC OFFENSIVE PLAYER OF THE WEEK AWARDS
| Year | Week | Opp. (Date) | Passing Statistics |
| 1998 | 11 | vs. NYJ (11/15) | 26-44, 59.1%, 276 yds., 3 TDs, 2 INT, 81.2 rtg. |
| 1999 | 3 | at S.D. (9/26) | 29-54, 53.7%, 404 yds., 2 TDs, 1 INT, 82.6 rtg. |
| 2000 | 4 | vs. Jac. (9/25) | 23-36, 63.9%, 440 yds., 4 TDs, 0 INT, 143.3 rtg. |
| 2000 | 17 | vs. Min. (12/24) | 25-36, 69.4%, 283 yds., 4 TDs, 1 INT, 118.2 rtg. |
| 2001 | 2 | vs. Buf. (9/23) | 23-29, 79.3%, 421 yds., 4 TDs, 2 INT, 129.6 rtg. |
| 2003 | 4 | at N.O. (9/28) | 20-25, 80.0%, 314 yds., 6 TDs, 0 INT, 158.3 rtg. |
| 2003 | 15 | vs. Atl. (12/14) | 25-30, 83.3%, 290 yds., 5 TDs, 0 INT, 146.5 rtg. |
| 2004 | 3 | vs. G.B. (9/26) | 28-40, 70.0%, 393 yds., 5 TDs, 0 INT, 140.9 rtg. |
| 2004 | 10 | vs. Hou. (11/14) | 18-27, 66.7%, 320 yds., 5 TDs, 2 INT, 115.7 rtg. |
| 2004 | 12 | at Det. (11/25) | 23-28, 82.1%, 236 yds., 6 TDs, 0 INT, 141.4 rtg. |
| 2004 | 16 | vs. S.D. (12/26) | 27-44, 61.4%, 383 yds., 2 TDs, 1 INT, 95.2 rtg. |
| 2005 | 9 | at N.E. (11/7) | 28-37, 75.7%, 321 yds., 3 TDs, 1 INT, 117.1 rtg. |
| 2006 | 2 | vs. Hou. (9/17) | 26-38, 68.4%, 400 yds., 3 TDs, 0 INT, 129.3 rtg. |
| 2006 | 7 | vs. Was. (10/22) | 25-35, 71.4%, 342 yds., 4 TDs, 0 INT, 140.4 rtg. |
| 2006 | 17 | vs. Mia. (12/31) | 22-37, 59.5%, 282 yds., 2 TDs, 0 INT, 101.4 rtg. |
| 2007 | 13 | vs. Jac. (12/2) | 20-29, 69.0%, 288 yds., 4 TDs, 1 INT, 126.1 rtg. |
| 2008 | 6 | vs. Bal. (10/12) | 19-28, 67.9%, 271 yds., 3 TDs, 0 INT, 134.7 rtg. |
| 2008 | 11 | vs. Hou. (11/16) | 30-46, 65.2%, 320 yds., 2 TDs, 0 INT, 99.9 rtg. |
| 2008 | 16 | at Jac. (12/18) | 29-34, 85.3%, 364 yds., 3 TDs, 0 INT, 140.7 rtg. |
| 2009 | 10 | vs. N.E. (11/15) | 28-44, 63.6%, 327 yds., 4 TDs, 2 INT, 97.4 rtg. |
| 2010 | 14 | at Ten. (12/9) | 25-35, 71.4%, 319 yds., 2 TDs, 0 INT, 118.6 rtg. |
| 2012 | 6 | at S.D. (10/15) | 24-30, 80.0%, 309 yds., 3 TDs, 1 INT, 129.0 rtg. |
| 2012 | 17 | vs. K.C. (12/30) | 23-29, 79.3%, 304 yds., 3 TDs, 0 INT, 144.8 rtg. |
| 2013 | 1 | Vs. Bal. (9/5) | 27-42, 64.3%, 462 yds., 7 TDs, 0 INT, 141.1 rtg. |